Van der Wiel scored his first goal of the season on Saturday as Ligue 1 leaders PSG thrashed Angers 5-1 to maintain their 21-point advantage at the summit.
The Dutch full-back completed the match at the Parc des Princes and Blanc has announced the 27-year-old was operated on a day later.
“Gregory had surgery on Sunday on his appendix,” coach Laurent Blanc said at Tuesday’s media conference. “It is not very serious, but unfortunately he will be out for a while.”
“Maybe for a few weeks.”
Van der Wiel will miss Wednesday’s Coupe de la Ligue semi-final against Toulouse, a game in which PSG also look set to be without Marco Verratti, Salvatore Sirigu and Thiago Silva.
By Taiwo Oyedeji
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