Anthony Martial is fit enough to start for Manchester United, with the French forward leading the line against Manchester City.
Martial missed United’s 2-1 win over Tottenham in midweek due to a muscle strain, but is back to boost Ole Gunnar Solskjaer’s options up top against the Premier League champions.
Luke Shaw has been handed a start at left-back, while Jesse Lingard’s resurgence continues with another start as Mason Greenwood and Ashley Young drop to the bench.
As for City, Pep Guardiola has elected to keep Fernandinho at centre-back, with Rodri in the middle alongside Kevin de Bruyne.
Sergio Aguero misses out as expected, with Gabriel Jesus leads the line – and Angelino starts at left-back with Benjamin Mendy on the bench.
Manchester United lineup: De Gea, Wan-Bissaka, Maguire, Lindelof, Shaw, McTominay, Fred, Lingard, James, Rashford, Martial
Subs: Romero, Tuanzebe, Williams, Young, Andreas, Mata, Greenwood
Manchester City lineup: Ederson, Walker, Stones, Fernandinho, Angelino, Rodri, D Silva, De Bruyne, Bernardo, Sterling, G Jesus.
Subs: Bravo, Gundogan, Mendy, Mahrez, Cancelo, Otamendi, Foden.
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